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With the initial-technology troponin assays, about 33% of sufferers presenting with signs and symptoms of acute coronary syndromes were being located to possess elevated troponin degrees inside the absence of elevated CK-MB concentrations.31 As assays are getting to be a lot more delicate, a good better quantity of people are actually recognized with elevated troponin levels. Even though the diploma of improvement will depend on the troponin assay employed, the Reduce-off values adopted plus the assay's sensitivity for CK-MB, the use of troponin as opposed to CK-MB has Evidently amplified a chance to detect myocardial injury secondary to ischemia Most likely approximately one hundred thirty%.
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